Clinical Specialty Divisions
Seventeen specialties, one translational platform. The division treating you is the division that developed the therapy.
Specialty divisions usually exist to organise referrals. These exist to keep development and treatment in the same hands. The physician assessing a patient for a retinal, neurological, or muscular indication works within the programme that built the construct for it, which means candidacy is judged against what the therapy actually does rather than against a summary of it.
That arrangement has an obvious failure mode, worth naming on the page rather than leaving for the reader to notice: a developer assessing candidacy for their own therapy has an interest in finding candidates. The safeguards are structural — pre-specified eligibility criteria, screening that excludes on objective findings, and independent review of protocol decisions — and they are described within each division rather than assumed.
Across all seventeen, the distinction between established and investigational care is maintained explicitly. Established treatment is offered as established treatment. Investigational work is identified as investigational, delivered under protocol, and is never the default answer to a clinical problem that has a conventional answer.
COMPREHENSIVE TRANSLATIONAL DEPARTMENTS
Clinical Divisions by Family
Interventional & Procedural Medicine
3 ProgramsMedical & Interventional Oncology
Putting therapy where it has to act.
Most cancer therapy fails at the point of delivery rather than the point of mechanism. A drug that works in the laboratory has to reach tumour tissue at sufficient concentration, and in hypovascular or fibrotic disease, systemic dosing raises whole-body exposure long before it raises intratumoural concentration. Image-guided intervention addresses that directly: a catheter in the vessel feeding a tumour, or a needle placed under CT guidance, achieves a local concentration unattainable systemically at any tolerable dose.
Scope of Care
- Image-guided ablation — radiofrequency, microwave, cryoablation
- Transarterial embolisation, chemoembolisation, and intra-arterial delivery
- Systemic oncological management and multidisciplinary planning
- Image-guided administration of investigational constructs
Neuro-Interventional Radiology
Endovascular access to an organ that systemic therapy reaches poorly.
Reaching the brain is the defining obstacle in neurological therapeutics. The blood-brain barrier that protects the central nervous system also excludes most of what might treat it, and systemic dosing high enough to overcome that exclusion carries whole-body exposure that is rarely acceptable.
Scope of Care
- Cerebral and spinal endovascular diagnosis and intervention
- Intra-arterial and intrathecal regional delivery
- Neurovascular disease management
- Procedural support for central nervous system protocols
Vascular & Body Interventional Radiology
Precision access, across the body.
Image-guided diagnosis and treatment throughout the body: biopsy, drainage, embolisation, ablation, and vascular access, alongside the management of peripheral arterial and venous disease.
Scope of Care
- Percutaneous biopsy, drainage, and ablation
- Embolisation and vascular access
- Peripheral arterial and venous disease intervention
- Critical limb ischaemia, including patients beyond revascularisation
Internal & Systemic Medicine
5 ProgramsInternal Medicine & Gene Therapy
Someone has to be responsible for the whole patient.
Gene therapy is usually organised around an indication, which leaves the patient divided between specialists who each own a part. This division owns the whole: the evaluation that determines whether an intervention is appropriate at all, the comorbidities and medications that determine whether it is safe, and the longitudinal follow-up that continues after the treating specialist has finished.
Scope of Care
- Comprehensive evaluation and candidacy assessment
- Pre-treatment screening: anti-vector antibody status, hepatic, renal, cardiac, immune
- Comorbidity and medication management around investigational treatment
- Long-term safety surveillance and follow-up
- Coordination between divisions and referring physicians
Cardiovascular Medicine
Perfusion as a delivery route.
Ischaemic heart disease, cardiomyopathy, and heart failure, including patients who have exhausted revascularisation. These patients share a problem that bypass and stenting do not solve: tissue that remains ischaemic because the microvasculature is inadequate, in people who are no longer candidates for a further mechanical intervention.
Scope of Care
- Ischaemic heart disease and refractory angina
- Cardiomyopathy and heart failure management
- Intramyocardial and intra-arterial construct delivery
- Non-viral angiogenic therapy with defined expression windows
- Perioperative and combined surgical-interventional planning
- Confirm before publication
- [CONFIRM: earlier drafts of this page named a "Cardiothoracic Surgery" division. If credentialed cardiothoracic or vascular surgeons are on staff, name them and the sites they operate at; a surgical division without identified surgeons is the first thing an institutional partner checks. If surgical capability is partnered rather than in-house, "Cardiovascular Medicine" as used here describes the actual scope accurately and should stand.]
Pulmonary Medicine
An organ that can be dosed directly.
Chronic obstructive disease, fibrotic lung disease, and pulmonary vascular disease, with conventional assessment and management alongside investigational work.
Scope of Care
- Obstructive and fibrotic lung disease assessment and management
- Pulmonary function and exercise physiology testing
- Inhaled and nebulised delivery of non-viral constructs
- Pulmonary vascular disease evaluation
Metabolic Medicine
Measured against the defect, not the diagnosis.
Insulin resistance, type 2 diabetes, fatty liver disease, and obesity-associated metabolic dysfunction.
Scope of Care
- Dynamic insulin sensitivity and glucose tolerance testing
- Continuous glucose monitoring and substrate utilisation studies
- Hepatic fat quantification and lipid subfraction analysis
- Metabolic protocol selection against measured baseline
Endocrinology
The transitions, not only the deficiencies.
Thyroid, adrenal, pituitary, and gonadal disorders, and the hormonal transitions of mid and later life.
Scope of Care
- Thyroid, adrenal, and pituitary disorders
- Hypogonadism and gonadal axis assessment
- Menopausal and andropausal transition management
- Hormonal contribution to metabolic and musculoskeletal decline
Neurological & Behavioural Medicine
3 ProgramsNeurology & Neuroscience
Mechanism-directed work in neurodegeneration.
Neurodegenerative disease — Alzheimer's disease, Parkinson's disease, ALS — alongside general neurological assessment and management.
Scope of Care
- Cognitive assessment and neurodegenerative evaluation
- Biomarker and neuroimaging interpretation
- Longitudinal neurological management
- Evaluation for investigational neurodegenerative protocols
Psychiatry & Mental Health
Conventional psychiatric care, delivered by a psychiatrist.
Psychiatric assessment and management, including mood and anxiety disorders, treatment-resistant presentations, and the psychiatric dimension of chronic and neurodegenerative illness — which frequently presents years before neurological signs appear, and is the reason this division sits beside neurology rather than apart from it.
Scope of Care
- Psychiatric assessment, diagnosis, and management
- Treatment-resistant mood and anxiety presentations
- Psychiatric care in chronic and neurodegenerative illness
- Coordination with neurology and addiction medicine
Addiction Medicine
Conventional treatment first, and optimised, before anything else is discussed.
Alcohol, opioid, and nicotine use disorder, with an emphasis on patients for whom approved pharmacotherapy and structured behavioural treatment have not produced durable remission.
Scope of Care
- Assessment and diagnosis of substance use disorder
- Approved pharmacotherapy and medically supervised withdrawal
- Structured behavioural treatment and relapse prevention
- Protocol evaluation for refractory presentations only
Sensory, Reproductive & Genetic Medicine
3 ProgramsOphthalmology
The most tractable target in the body.
Inherited and acquired retinal disease, with emphasis on conditions where gene-directed treatment is established or in development.
Scope of Care
- Inherited retinal disease genotyping and phenotyping
- Structural and functional retinal assessment
- Subretinal and intravitreal administration
- Candidacy assessment based on residual retinal architecture
Reproductive Medicine
Organic presentations with an identifiable failed pathway.
Erectile dysfunction, hypogonadism, infertility, polycystic ovary syndrome, and endometriosis.
Scope of Care
- Male and female reproductive endocrine assessment
- Organic versus non-organic erectile dysfunction characterisation
- Infertility evaluation and management
- PCOS and endometriosis assessment
Medical Genetics
The question that precedes every other decision here.
Diagnostic genomic evaluation, variant interpretation, and family assessment.
Scope of Care
- Diagnostic genomic sequencing and variant interpretation
- Carrier and family cascade assessment
- Genetic counselling
- Determination of genotype-based protocol eligibility
Immune, Musculoskeletal & Regenerative Medicine
3 ProgramsImmunology & Immunoscience
Central tolerance, and the organ that maintains it.
Immunosenescence, autoimmune disease, and the restoration of immune competence.
Scope of Care
- Immunosenescence assessment: naive T-cell fraction, TREC, repertoire diversity
- Autoimmune disease evaluation and management
- Immune reconstitution protocols
- Thymic assessment and image-guided intrathymic delivery
Musculoskeletal Medicine
Function, not mass.
Sarcopenia, tendon and joint degeneration, and age-related loss of strength and mobility.
Scope of Care
- Functional assessment: isokinetic strength, gait speed, SPPB, chair-rise
- Sarcopenia diagnosis by EWGSOP2 criteria
- Tendon and joint degenerative disease
- Construct-matched outcome assessment in treated muscle groups
Regenerative Cell Therapy
A product that can be tested before it is given.
Cell-based treatment using multilineage stress-enduring cells and their secreted factors, across orthopaedic, ischaemic, and inflammatory indications.
Scope of Care
- Cell therapy for orthopaedic and degenerative indications
- Secretome and exosome-based protocols
- Product characterisation and release testing
- Distinction between engraftment-dependent and paracrine mechanisms
Refer a Patient or Initiate Clinical Candidacy Assessment
Referring clinicians can submit patient records, diagnostic imaging, and molecular pathology securely for multidisciplinary review by our departmental chiefs.